BLOOD RECOVERY
SYSTEMS, INC
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Osteogenesis distraction and platelet-rich plasma
for bone restoration of the severely atrophic mandible: preliminary
results
Robiony M, Polini F, Costa F, Politi M. Department of Maxillo-Facial Surgery, Faculty of Medicine, University of Udine, Udine, Italy. massimo.robiony@med.uniud.it PURPOSE: The purpose of this study was to evaluate a new method of restoring severe atrophic mandible using platelet-rich plasma (PRP) during distraction osteogenesis. MATERIALS AND METHODS: Since 1999, 2 men and 3 women with severe atrophy (Cawood and Howell classes V and VI) of a completely edentulous mandible have been treated with a novel distraction procedure. During the surgery, a mixture of autologous bone graft, harvested from the iliac crest, and an autologous platelet concentrate, obtained from platelet-rich plasma, filled the distraction gap. This mixture constituted an autologous bone-platelet gel that was used to create a useful bony scaffold for distraction regenerate. After a latency period of 15 days, a distraction run of 0.5 mm/d, and a 60-day period of consolidation, the distraction device was removed and implants were placed simultaneously. RESULTS: In all treated patients, planned distraction height was achieved with a considerable enhancement of bony regeneration, and in all cases it was possible to place implants at a planned time. CONCLUSIONS: The combination of these recent and innovative regenerative methods seems to be effective in restoring the severe atrophic mandible. Copyright 2002 American Association of Oral and Maxillofacial Surgeons J Oral Maxillofac Surg 60:630-635, 2002 >> full article |